Hi, I quite understand the mechanism of telomere replication, but there are two main concepts that I haven't yet understood.

by Amal
(CA - US)

Please try your best to explain them in a methodical, clear manner as it was hard to understand them from Wikipedia and other sources.

1) why is there a need for telomere replication? I mean, there is supposedly telomeres at the end of every chromosome that get complementary strands through telomerase, and what basically happens to the replicated telomeres ?

2) how do telomeres deteriorate or get consumed ? ( aren't they needed to prevent the shortening of the newly synthesized DNA strand ?) . Thanks !

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