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Prion Diseases
A Short Review



Our Biology Book




What is a Prion? Learn Below






1. What is a prion?

A prion is an infectious (transmissible) protein able to replicate by transforming other proteins into a copy of the prion. The mechanism of copying is not yet understood by science.

The hypothesis come out from research about a nervous system disease known as Creutzfeldt-Jacob disease, epidemiologically associated to a bovine disease called bovine spongiform encephalitis (the mad cow disease). Research discovered that the infectious agent that causes those diseases, suprisingly, was a protein capable of copying itself and of being transmitted by ingestion (the reason why meat from contaminated animals cannot be consumed), inoculation and even heredity.

Image Diversity: prion



2. What are the main human diseases caused by prions?

The main known human diseases of such type are the Creutzfeldt-Jacob disease (CJD), the kuru and the Gerstmann-Sträussle-Scheinken disease (GSS). The hypothesis that many other diseases of unknown etiological agents are actually caused by self-replicating infectious proteins is strong.

Image Diversity: mad cow disease




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