Which fact is most important in explaining how enzymes speed reactions?

Very low potential energy tends to make molecules unstable.
High-energy collisions are less common than low-energy collisions.
It takes less energy to break a hydrogen bond than a covalent bond.
Large molecules collide more energetically than small molecules.
Every reaction step adds to the time required for the overall reaction.

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Enzymes
by: michael

High-energy collisions are less common than low-energy collisions.

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