Why does pyruvate have low fermentation rate?

by Gordon
(Maine)

Pyruvate is a substrate for the enzyme pyruvate decarboxylase that makes acetaldehyde and CO2 in yeast. There are two plausible explanations for the low rate of fermentation in this tube- can you figure out what they might be? Are they mutually exclusive?

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Pyruvate Decarboxylase
by: Anonymous

Mate I've got to say this is the first question today I really don't know answer. I can tell you what I know about pyruvate decarboxylase: this enzyme requires coenzyme thyamine pyrophosphate (TPP)which is derived from vitamin B1. Maybe limitation of this vitamin in the organism can be reason. I'm little surprised about this question because I know TPP doesn't work slowly.

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